
Cheap Homes for Rent in Medical Center Neighborhood of San Antonio, TX from $600 (29 Rentals)
Search the lowest-cost Homes available for rent right now in the Medical Center area of San Antonio.


3607 Rock Creek Run

4803 Hamilton Wolfe Rd

6007 Grissom Rd

6007 Grissom Rd

2502 Babcock Rd, Unit Residence at Medical - 1 Bedroom

8655 Datapoint Dr
What Does “Rent Burdened” Mean? How Much Rent Is Too Much
Learn the official definition (spending 30% or more of your gross income on housing) and how to calculate your exact rent-to-income ratio. This guide offers expert tips on factoring in total housing costs (including utilities and fees) and budgeting accurately to avoid unnecessary financial strain.

6201 Grissom Rd

7500 Callaghan Rd, Unit 168A

4212 Medical Dr, Unit 1414

4119 Medical Dr

8633 Datapoint Dr

2502 Babcock Rd, Unit Residence at Medical - 2 Bedroom 1 Bath

4803 Hamilton Wolfe
Your Guide to Co-Signers: The Risks, Rewards, and Everything in Between
Thinking about getting a co-signer for your rental application? We break down what a co-signer is, the potential benefits, and the serious risks for both parties. Find out if it's the right choice for you.

4803 Hamilton Wolfe

8642 Fredericksburg Rd

4119 Medical Dr

4107 Medical Dr

8611 Datapoint Dr

6201 Grissom Rd

4212 Medical Dr
Roommate Matching: Finding the Right Fit and Avoiding Pitfalls
When searching for a roommate, follow this list of essential steps and set clear expectations to create a solid foundation for a harmonious living situation.

9835 Fredericksburg Rd, Unit 1324

9835 Fredericksburg Rd, Unit 634

2502 Babcock Rd, Unit Residence at Medical - 2 Bedroom 2 Bath

5322 Medical Dr, Unit B-202

7802 Richard Frank Way

7802 Richard Frank Way

9835 Fredericksburg Rd, Unit 423
Discover the SATX Local Vibe: An Insiders Look Into the Life of Renting in San Antonio
Go beyond the Alamo with a local expert's guide to San Antonio's best. Explore vibrant neighborhoods for renting, iconic Tex-Mex food, deep history, and hidden green spaces in the River City.

4803 Hamilton Wolfe Rd, Unit 310, Unit 310
Medical Center, San Antonio, TX Local Guide

How much does it cost to rent a home in Medical Center?
| Bedroom | Average Rent | Cheapest Rent | Highest Rent |
|---|---|---|---|
| Medical Center 2 Bedroom Homes for Rent | $1,391 | $925 | $2,500 |
| Medical Center 3 Bedroom Homes for Rent | $1,887 | $1,350 | $3,800 |
| Medical Center 4 Bedroom Homes for Rent | $2,038 | $1,700 | $2,450 |
Browse Homes for Rent in this Neighborhood
There are currently 29 rentals with your search options within a 2 mile radius of the Medical Center Neighborhood of San Antonio, TX.
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Medical Center, San Antonio, TX Local Guide
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Cheapest Available Medical Center Apartments for Rent
 The cheapest available apartment rental in the Medical Center area of San Antonio, TX is a Studio unit found at The Riley priced from $550. Station at Elm Creek has the second lowest priced unit, which is a Studio apartment currently listed from $595. Here are the most affordable Medical Center apartments for rent in San Antonio, TX:
| Apartment Listing | Model Name | Bed/Bath | Priced From |
|---|---|---|---|
| The Riley | S1 | Studio,1BA | $550 |
| Station at Elm Creek | Studio Renovated | Studio,1BA | $595 |
| Altitude | Studio | Studio,1BA | $605 |
| The Branch at Medical Center | E1-D | Studio,1BA | $616 |
| Villas of Oak Creste | 1A | 1BR,1BA | $625 |
| The Oaks Apartments At Medical Center | OMCA2 | 1BR,1BA | $625 |
| Windbury Apartments | The Ayers | 1BR,1BA | $630 |
| Valor Hill Apartments | A | Studio,1BA | $640 |
| The Edge Apartments | E1-0B1B | Studio,1BA | $645 |
| Torino Villas Apartments | A1 1/1-Reno | 1BR,1BA | $649 |
Best Value Apartments for Rent in Medical Center, TX
As of April 18, 2026 the best value apartment in the Medical Center area is the $0.70 price per square foot 3x3 C TH Model at The Iris Apartments in the in the Oakland Estates neighborhood starting from $1,102. The second greatest value Medical Center apartment is the I1 Model at City Summit Apartments starting at $1,408 with a $0.93 price per square foot in the Outer Northwest Side neighborhood. Here is today’s list of the best values for Medical Center apartments based on price per square foot:
| Apartment Listing | Model Name | Bed/Bath | Price Per Sq.Ft. |
|---|---|---|---|
| The Iris Apartments | 3x3 C TH | 3BR,3BA | $0.70 |
| City Summit Apartments | I1 | 3BR,2.5BA | $0.93 |
| Amber Hill | 3 Bedroom 2 Bath | 3BR,2BA | $1.06 |
| Hunter's Glen Apartments | 2 Bedroom / 2 Bath | 2BR,2BA | $1.04 |
| Plaza DeVille | Willow | 2BR,2BA | $1.15 |
| Apartments 36 | 1 Bedroom One Bathroom | 1BR,1BA | $0.99 |
| The Fredd | Astaire | 1BR,1BA | $1.15 |
| Serenity Residences (Medical Center) | A2 - PR | 1BR,1BA | $1.03 |
| Barcelo Apartments | A1 | 1BR,1BA | $1.08 |
| The Riley | S1 | Studio ,1BA | $1.14 |
10 Hidden Costs of Renting You Should Budget for Before Signing a Lease
Avoid financial stress when renting. Learn about the 10 most common hidden costs—from pet fees to utilities—you must budget for before you sign a lease.
Read ArticleDon't Settle: How to Negotiate Your Apartment Lease and Save Money
Discover the insider tips from an attorney and real estate agent on how to negotiate your next apartment lease. Find out what's on the table and what's not, so you can save money and get the best terms possible.
Read ArticleLive and Work: Best San Antonio Neighborhoods for Rent by Employer
Looking for an apartment in San Antonio? Discover the best neighborhoods to rent near major employers like HEB, USAA, and the Medical Center. Find the perfect fit for your commute and lifestyle.
Read ArticleThe Ultimate Long-Distance Moving Checklist: Tips from a Real Estate Pro
Moving is tough, especially long-distance. Learn how to minimize stress & expenses with proven strategies from a real estate pro, covering everything from logistics to finances.
Read ArticleCash or credit? Understanding the Importance of Credit Score in Real Estate and Renting
Discover how your credit score impacts your ability to lease or buy a home. Learn how credit scores are determined, how to check yours, and strategies to improve it for real estate success.
Read ArticleLocal Expert's Guide To the Best Student Friendly Neighborhoods to Rent Near Colleges in San Antonio
A Local Experts guide to the Best Student Friendly Neighborhoods Near Colleges in the San Antonio metro area. Find your perfect SATX Student apartment, condo, or rental home today at ApartmentHomeLiving.com
Read ArticleQuick Rent Budget Calculator
How much rent can you afford?
The common "Rule of Thumb" is that rent should be no more than 30% of your income. How much is that? Enter your monthly income and click "Calculate My Budget" to find out.
Best Local Schools in Medical Center, San Antonio, TX
School data provided by Great Schools
Frequently Asked Questions about Medical Center
What type of rentals are currently available in Medical Center?
There are currently 195 Apartments for Rent in Medical Center, TX with pricing that ranges from $550 to $4,043. There are also 126 Single Family Homes for rent, Condos, and Townhome rentals currently available in Medical Center ranging from $235 to $3,800.
What is the current price range for Rental Homes in Medical Center?
Today's rental pricing for Homes for Rent, Condos and Townhomes in Medical Center ranges from $235 to $3,800 with an average monthly rent of $1,642.
How much are larger Three and Four Bedroom Rentals in Medical Center?
For those who are looking for larger living arrangements, Three Bedroom Apartments in Medical Center range from $1,136 to $3,604, while Three Bedroom Homes, Condos, and Townhomes for rent range from $1,350 to $3,800. Four Bedroom Single-Family rentals are also available starting from $1,700 and Four Bedroom Apartments start at $1,850.
Expert Rental Resources
The rental experts at ApartmentHomeLiving.com provide you with top advice, tools, and tips for understanding the leasing process and finding the perfect rental. Here are a few helpful rental and leasing articles from our experts to guide you on your search.
Helpful Local Expert Guides

A Texas Local Expert’s Guide To the 10 Top Budget-Friendly Neighborhoods to Rent in San Antonio
Written by: Rhonda R Fletcher
I'm Rhonda, your ApartmentHomeLiving.com Local Expert for San Antonio, Texas. Welcome to San Antone', the smallest big city in Texas. San Antonio has been a part of my life for as long as I can remember.

Local Guide To the Best Student Friendly Neighborhoods to Rent Near Colleges in San Antonio
Written by: Rhonda R Fletcher
Hi, I'm Rhonda, your ApartmentHomeLiving.com Local Expert and your guide to places to live around San Antonio colleges and universities. San Antonio, Texas, is one of the most dynamic cities in the Southwest.

Live and Work: Best San Antonio Neighborhoods for Rent by Employer
Written by: Rhonda R Fletcher
Hello, I'm Rhonda, your ApartmentHomeLiving.com Local Expert for San Antonio, Texas. San Antonio has always been a major part of my life. I'm glad to share my thoughts with you.

Discover the SATX Local Vibe: An Insiders Look Into the Life of Renting in San Antonio
Written by: Rhonda R Fletcher
Remember the Alamo? Who could forget, right? But what else does the historic San Antonio, Texas, have to offer besides this national park complex? Hi! I'm Rhonda, your ApartmentHomeLiving.com Local Expert on San Antonio.
Articles, How-To's, and Tips

What Does “Rent Burdened” Mean? How Much Rent Is Too Much
Written by: Lauren Harrington
This article draws from first-hand renter experiences and recurring financial challenges reported after moving in.

Maximizing Your Refund: Essential Tax Tips for Renters
Written by: Christine Leonard, Esq.
Other than tax professionals, I can’t think of anyone who looks forward to tax season. For everybody else, April is a stressful month to collect information and meet deadlines.

18 Must-Ask Rental Tour Questions That Reveal the Truth about a Property
Written by: Lauren Harrington
Renting your next home can feel thrilling and overwhelming at the same time.

A Renters Guide for Tips on Writing Your Notice for Not Renewing Your Apartment
Written by: Bob Mallory
Packing up everything you own to move is so stressful for many that ending your apartment lease can feel like a small or unimportant task. Ending your lease involves more than simply turning over your keys on the last day.