
2 Bedroom Apartments for Rent in the South Main Neighborhood of Houston, TX (55 Rentals)


The Fountains at Almeda

Orleans at Fannin Station

Nantucket at Fannin Station

Advenir at The Med Center

6Ten at Med Center Apartments

The Huxley at Medical Center

Oaks of Charleston

Villa Solano Apartments
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Regards at Med Center

Beacon at Buffalo Pointe

Aspire at 610

Connection at Buffalo Pointe Apartments

Melia Medical Center

Cypress Creek at Reed Road Apartment Homes

Mariposa at Reed Road 55+ Apartment Homes

2826 S Bartell Dr, Unit F23

4045 W Bellfort Ave
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Touring a rental? This guide helps you know exactly what to look for, from safety features to hidden flaws, so you can confidently sign your lease or keep searching.

8433 Hearth Dr

2818 S Bartell Dr

806 Holmes Rd

2826 S Bartell Dr

2830 S Bartell Dr

8517 Hearth Dr

1367 S Loop W

11315 Main St
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3501 Link Valley Dr.

2806 Grand Fountains Dr

9707 Timberside Dr, Unit 02

The Citadel at Med Center Houston Apartments

9707 Timberside Dr, Unit 9

9707 Timberside Dr, Unit 31

9707 Timberside Dr, Unit 35
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9707 Timberside Dr, Unit 40

9707 Timberside Dr, Unit 17-R

9707 Timberside Dr, Unit 45

9707 Timberside Dr, Unit 19-R

2401 Westridge St, Unit 2-2314

2401 Westridge St, Unit 2-2617

2401 Westridge St, Unit 2-2610

2400 S Loop W, Unit 1-1501

2401 Westridge St, Unit 2-2710

2401 Westridge St, Unit 2-2009
Houston's Best Affordable Neighborhoods
Learn about Houston and the best places to live with original content written by our Houston Local Expert Lori Rosario
South Main, Houston, TX Local Guide

How much does it cost to rent an apartment in South Main?
Bedroom | Average Rent | Cheapest Rent | Highest Rent |
---|---|---|---|
South Main Studio Apartments | $1,100 | $829 | $1,321 |
South Main 1 Bedroom Apartments | $1,256 | $497 | $1,991 |
South Main 2 Bedroom Apartments | $1,634 | $601 | $2,719 |
South Main 3 Bedroom Apartments | $1,960 | $1,490 | $3,499 |
South Main 4 Bedroom Apartments | $1,664 | $1,664 | $1,664 |
Browse Apartments in this Neighborhood
There are currently 55 rentals with your search options within a 2 mile radius of the South Main Neighborhood of Houston, TX.
See all Apartments in HoustonExplore Houston
Largest Available South Main 2 Bedroom Apartments
The largest available 2 Bedroom apartment unit in the South Main area of Houston, TX is found at Regards at Med Center and is listed at 1,418 square feet priced from $1,875. Here is today’s list of the largest available 2 Bedroom units in the area:
Apartment Listing | Model Name | Square Footage | Priced From |
---|---|---|---|
Regards at Med Center | B5 | 1,418 Sq Ft | $1,875 |
Aspire at 610 | B3 | 1,274 Sq Ft | $1,864 |
Orleans at Fannin Station | B4 | 1,253 Sq Ft | $2,099 |
Nantucket at Fannin Station | C2 | 1,250 Sq Ft | $1,859 |
Melia Medical Center | B3 | 1,223 Sq Ft | $1,542 |
The Fountains at Almeda | Augusta | 1,147 Sq Ft | $1,700 |
Charleston at Fannin Station | B2 | 1,108 Sq Ft | $2,024 |
Beacon at Buffalo Pointe | B2 | 1,105 Sq Ft | $1,776 |
Mariposa at Reed Road 55+ Apartment Homes | Dorsey | 1,075 Sq Ft | $601 |
Cypress Creek at Reed Road Apartment Homes | Trinity | 1,049 Sq Ft | $601 |
Cheapest Available South Main 2 Bedroom Apartments
Currently the lowest priced 2 Bedroom apartment unit South Main of Houston, TX is the Trinity Model starting from $601 at Cypress Creek at Reed Road Apartment Homes. The average price for all 2 Bedroom apartments in South Main is currently $1,634. Here is today’s list of the cheapest available 2 Bedroom options in the area:
Apartment Listing | Model Name | Priced From |
---|---|---|
Cypress Creek at Reed Road Apartment Homes | Trinity | $601 |
Mariposa at Reed Road 55+ Apartment Homes | Dorsey | $601 |
Alegria II | 2X1 RENO | $999 |
Oaks of Charleston | B3 | $1,045 |
Ashford Santa Fe | 2X1A | $1,049 |
Villa Solano Apartments | 2x1A Renovated 830 sq ft | $1,149 |
The Huxley at Medical Center | B3- Classic Unit | $1,163 |
Connection at Buffalo Pointe Apartments | B2 | $1,358 |
Advenir at The Med Center | Tahoe | $1,399 |
Melia Medical Center | B3-EH | $1,542 |
Getting Around the South Main Neighborhood in Houston, TX
Walk Score®
39 / 100
Car-Dependent
Most errands require a car
Bike Score®
42 / 100
Somewhat Bikeable
Minimal bike infrastructure
Transit Score®
47 / 100
Some Transit
A few nearby public transportation options
What Are Walk Score®, Transit Score®, and Bike Score® Ratings?
- Walk Score® measures the walkability of any address.
- Transit Score® measures access to public transit.
- Bike Score® measures the bikeability of any address.
Frequently Asked Questions about 2 Bedroom South Main Apartments
What is the Cheapest apartment in South Main with 2 Bedroom?
Currently the most affordable 2 Bedroom in South Main is at Cypress Creek at Reed Road Apartment Homes listed at $601.
How much is the average rent for a 2 Bedroom South Main Apartment?
The average rent for a 2 Bedroom Apartment in South Main is $1,634.
What is the largest available 2 Bedroom South Main Apartment for rent?
Today's apartment with the most square footage in South Main is a 1,418 square feet unit starting from $1,875 at Regards at Med Center.
What is the average size for South Main 2 Bedroom Apartments for rent?
The average size for a 2 Bedroom rental in South Main is currently 880 sq ft.
Expert Rental Resources
Helpful Apartment Articles, How-To's and Tips
The rental experts at ApartmentHomeLiving.com provide you with top advice, tools, and tips for understanding the leasing process and finding the perfect rental. Here are a few helpful rental and leasing articles from our experts to guide you on your search.

The 10 Best Affordable Neighborhoods in Houston, TX
Written by: Lori Rosario
Houston is a huge city, and it’s still growing, which makes it one of the most sought after places in the country to move.

Roommate Matching: Finding the Right Fit and Avoiding Pitfalls
Written by: Cheryl Bowman
A fantastic way to save money and enjoy a built-in community is to share an apartment. However, a bad roommate situation can turn your dream rental into a nightmare.

The Art of the Rental Viewing: What to look for during a property tour
Written by: Marie Brown
You’ve scrolled through countless listings, walked through a blur of rentals, and finally found what feels like the one. The pictures? Fantastic. The neighborhood seems just right.

Know Your Budget: Calculating What You Can Realistically Afford When Renting
Written by: Lauren Harrington
Renting an apartment or house isn’t just about looking through online ads, choosing a few apartments or homes you want to tour, filling out an application, and putting down a deposit. Those things are all necessary and important.