
Cheap Apartments for Rent in the South Main Neighborhood of Houston, TX from $400 (36 Rentals)
Search the lowest-cost Apartments available for rent right now in the South Main area of Houston.


The Huxley at Medical Center

Oaks of Charleston

2818 S Bartell Dr

Villa Solano Apartments

6Ten at Med Center Apartments

Cypress Creek Reed Road

Connection at Buffalo Pointe Apartments

2701 W Bellfort Ave
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Advenir at The Med Center

Total Monthly Price
Nantucket at Fannin Station

Total Monthly Price
Lakes at 610

Beacon at Buffalo Pointe

Total Monthly Price
Regard at Med Center

Allora Med Center

Aspire at 610

Total Monthly Price
Charleston at Fannin Station

Ashford Santa Fe
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Pine Terrace

3811 Link Valley

2826 S Bartell Dr

2824 S Bartell Dr

2820 S Bartell Dr

2818 S Bartell Dr

New Hope Housing on Reed

Alegria II

The Citadel at Med Center Houston Apartments
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Saphira Apartments

2816 S Bartell Dr

2830 S Bartell Dr, Unit 311, Unit 311

8421 Hearth Dr

8519 Hearth Dr, Unit 26, Unit 26

8433 Hearth Dr, Unit 1, Unit 1

2826 S Bartell Dr, Unit 37, Unit 37

9707 Timberside Dr

2822 S Bartell Dr, Unit 38, Unit 38
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South Main, Houston, TX Local Guide

How much does it cost to rent an apartment in South Main?
| Bedroom | Average Rent | Cheapest Rent | Highest Rent |
|---|---|---|---|
| South Main Studio Apartments | $1,019 | $779 | $1,145 |
| South Main 1 Bedroom Apartments | $1,284 | $497 | $2,451 |
| South Main 2 Bedroom Apartments | $1,668 | $984 | $2,632 |
| South Main 3 Bedroom Apartments | $1,933 | $1,290 | $4,413 |
| South Main 4 Bedroom Apartments | $1,663 | $1,663 | $1,663 |
Browse Apartments in this Neighborhood
There are currently 36 rentals with your search options within a 2 mile radius of the South Main Neighborhood of Houston, TX.
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Cheapest Available South Main Apartments for Rent
 The cheapest available apartment rental in the South Main area of Houston, TX is a 1 Bed unit found at The Huxley at Medical Center priced from $602. Pine Terrace has the second lowest priced unit, which is a Studio apartment currently listed from $755. Here are the most affordable South Main apartments for rent in Houston, TX:
| Apartment Listing | Model Name | Bed/Bath | Priced From |
|---|---|---|---|
| The Huxley at Medical Center | A1- Classic Unit | 1BR,1BA | $602 |
| Pine Terrace | Efficiency | Studio,1BA | $755 |
| Oaks of Charleston | Efficiency | Studio,1BA | $779 |
| Ashford Santa Fe | 1X1-U | 1BR,1BA | $799 |
| Villa Solano Apartments | 1x1C Renovated 670 sq ft | 1BR,1BA | $799 |
| 6Ten at Med Center Apartments | 1x1 | 1BR,1BA | $845 |
| Mariposa at Reed Road 55+ Apartment Homes | Miller | 1BR,1BA | $877 |
| Cypress Creek Reed Road | Brazos | 1BR,1BA | $917 |
| Advenir at The Med Center | Norfolk | 1BR,1BA | $1,029 |
| Nantucket at Fannin Station | A2 | 1BR,1BA | $1,083 |
Best Value Apartments for Rent in South Main, TX
As of April 11, 2026 the best value apartment in the South Main area is the $1.24 price per square foot 3X2-D Model at Ashford Santa Fe in the in the South Main neighborhood starting from $1,549. The second greatest value South Main apartment is the B1 Model at Orleans at Fannin Station starting at $1,788 with a $1.52 price per square foot in the South Main neighborhood. Here is today’s list of the best values for South Main apartments based on price per square foot:
| Apartment Listing | Model Name | Bed/Bath | Price Per Sq.Ft. |
|---|---|---|---|
| Ashford Santa Fe | 3X2-D | 3BR,2BA | $1.24 |
| Orleans at Fannin Station | B1 | 2BR,2BA | $1.52 |
| The Huxley at Medical Center | B1- Classic Unit | 2BR,2BA | $1.38 |
| Mariposa at Reed Road 55+ Apartment Homes | Miller | 1BR,1BA | $1.15 |
| Connection at Buffalo Pointe Apartments | A2 | 1BR,1BA | $1.62 |
| Cypress Creek Reed Road | Brazos | 1BR,1BA | $1.29 |
| Villa Solano Apartments | 1x1D Renovated 700 sq ft | 1BR,1BA | $1.50 |
| Nantucket at Fannin Station | A2 | 1BR,1BA | $1.62 |
| Advenir at The Med Center | Norfolk | 1BR,1BA | $1.73 |
| Oaks of Charleston | Efficiency | Studio ,1BA | $1.56 |
Frequently Asked Questions about Cheap South Main Apartments
How much is rent for a Cheap One Bedroom South Main Apartment?
The lowest price for a Cheap One Bedroom South Main Apartment is $602 at The Huxley at Medical Center.
What is the lowest price for a Cheap Two Bedroom South Main Apartment for rent?
Today's best deal for a Cheap Two Bedroom Apartment in South Main is starting from $980 at Ashford Santa Fe.
What is the most affordable South Main Three Bedroom Apartment?
The best deal on a cheap South Main Three Bedroom Apartment rental is at Cypress Creek Reed Road and starts from $1,290.
Expert Rental Resources
The rental experts at ApartmentHomeLiving.com provide you with top advice, tools, and tips for understanding the leasing process and finding the perfect rental. Here are a few helpful rental and leasing articles from our experts to guide you on your search.
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